Metabolomic and Proteomic Profile of Dried Hop Inflorescences (Humulus lupulus L. cv. Chinook and cv. Cascade) by SPME-GC-MS and UPLC-MS-MS

Hop (Humulus lupulus L.) is grown mainly for the production of beer. The flowers female plant give it bitter taste and pungent aroma. There are a large number hop varieties differing in their ?-acid content, essential oil levels odor profiles. Aside from use brewing, more recently, hops have been used pharmacological properties its derivatives that great importance to pharmaceutical industry. known fairly complex chemistry characterized by presence variety sesquiterpenoids, diterpenoids triterpenoids, phytoestrogens flavonoids. Additionally, considering countless applications sector recent years, chemical characterization different cultivars better identify source specific secondary metabolites. For this purpose, dried inflorescences two cultivars, Chinook Cascade, were investigated using Solid-Phase Microextraction-Gas Chromatography-Mass Spectrometry Liquid Chromatography-Tandem Mass (SPME-GC-MS LC-MS-MS) describe metabolomic proteomic profile. Furthermore, thanks an in-depth statistical survey, was possible carry out comparative study highlighting interesting implications deriving investigative study.